Laboratory for Bio Architecture

2025

Kengo Miyoshi, Masatomo Chikamori, Takashi Ando, Kengo Nakata, Tomohisa Aoyama, Yukiko T Matsunaga, Toshimasa Yamauchi, "Quantitative Image Analysis of Nailfold Capillaries during an In-hospital Education Program for Type 2 Diabetes or Obesity", Microvas Res, 161 (2025), 104830.
DOI: 10.1016/j.mvr.2025.104830
Y. Ikeda, M Kondo, J.I. Suehiro, H. Oshima, S.Y. Kok, K. Takahashi, J. Pauty, D. Wang, H. Sakurai, T. Watabe, M. Oshima, Y.T. Matsunaga, "Tumor-microvessel on-a-chip reveals sequential intravasation cascade of cancer cell clusters", iScience (2025), 112517.
DOI: 10.1016/j.isci.2025.112517
J. Cacheux, T. Quénan, D. Alcaide, J. Ordonez-Miranda, L. Jalabert, S. Nakano, M. Nakanishi, P. Cordelier, A. Bancaud, Y.T. Matsunaga, "Monitoring the poroelastic response of collagen gels with embedded senescent fibroblasts reveals tissue softening associated with collagen network reorganization”, bioRxiv (2025)
DOI: 10.1101/2025.04.18.649513
松永行子, "組織工学的手法を用いた多細胞組織の構築", 実験医学 4月号, Vol.43, No.6, (2025) 874-878.
DOI: 10.18958/7691-00001-0001879-00
Hedele Zeng, Takanori Sano, Jun-ichi Kawabe, Yukiko T. Matsunaga, "Spatiotemporal analysis of pericyte-induced dynamics in nascent angiogenic morphogenesis and heterogeneity using a microvessel-on-a-chip platform", bioRxiv (2025)
DOI: 10.1101/2025.02.02.634898
A. Bancaud, T. Nakajima, J.I. Suehiro, B. Alric, F. Morfoisse, J. Cacheux, Y.T. Matsunaga, "Intraluminal pressure triggers a rapid and persistent reinforcement of endothelial barriers", Lab on a Chip (2025) 2061–2072.
DOI: 10.1039/D5LC00104H

2024

K. Noda, T. Kasama, M. Shinohara, H. Masakaze, Y.T. Matsunaga, M. Takai, Y. Ishii, R. Miyake, "Hollow fiber microreactor combined with digital twin to optimize the antimicrobial evaluation process", Micromachines 15 (2024) 1517.
DOI: 10.3390/mi15121517
近藤誠, 安部和弥, 松永行子, "三次元微小血管モデルを用いた組織構築による疾患・生体現象の解明"（特集号：血管・リンパ管研究の最前線と治療への展開）, 医学のあゆみ, (2024) Vol. 289, No. 13, 1089-1092.
https://www.ishiyaku.co.jp/search/details.aspx?bookcode=286840
D. Alcaide, B. Alric, J. Cacheux, S. Nakano, K. Doi, M. Shinohara, M. Kondo, A. Bancaud, Y.T. Matsunaga, "Laminin and hyaluronan supplementation of collagen hydrogels enhances endothelial function and tight junction expression on three-dimensional cylindrical microvessel-on-a-chip", BBRC, 724 (2024) 150234.
DOI: 10.1016/j.bbrc.2024.150234
篠原満利恵, 高橋幹徳, 笠間敏博, 三宅亮, 松永行子, "生体模倣システムのための液体分注システムの開発", 生産研究, 76(2), 117-119 (2024).
DOI: 10.11188/seisankenkyu.76.117
近森正智, 高橋和樹, 松永行子, "臓器連関から紐解く腫瘍進展機構の解析", 医学のあゆみ, (2024) 289, 195-200.
https://webview.isho.jp/journal/detail/pdf/10.32118/ayu28903195
三好建吾, 近森正智, 青山倫久, 松永行子, 山内敏正, "2 型糖尿病患者・肥満患者における病態と爪郭毛細血管の定量評価の関連について", デサントスポーツ科学, 45 (2024) 169-176.
DOI: 10.57488/descente.45.0_169
J. Cacheux, T. Nakajima, D. Alcaide, T. Sano, K. Doi, A. Bancaud, Y.T. Matsunaga, "Protocol for fabricating and characterizing microvessel-on-a-chip for human umbilical vein endothelial cells", STAR Protocols, 5(2024), 102950.
DOI: 10.1016/j.xpro.2024.102950
Y. Ikeda, H. Oshima, S.Y. Kok, M. Oshima, Y.T. Matsunaga, "Spatiotemporal observation reveals metastatic tumor-driven vascular remodeling as a potential route to polyclonal colonization", Nano Biomedicine, 16, 19-27 (2024)
DOI: 10.11344/nano.16.19

2023

H Zeng, T Sano, J Cacheux, A Bancaud, JI Kawabe, YT Matsunaga, "Capillary stem cells enhance vascular barrier function revealed by the in vitro microvessel model", Nano Biomedicine, 2023.
DOI: 10.11344/nano.15.105
K Takahashi, M Kobayashi, H Katsumata, S Tokizaki, T Anzai, Y Ikeda, DM Alcaide, K Maeda, M Ishihara, K Tahara, Y Kubota, F Itoh, J Park, K Takahashi, YT Matsunaga, Y Yoshimatsu, KA Podyma-Inoue, T Watabe, "CD40 is expressed in the subsets of endothelial cells undergoing partial endothelial–mesenchymal transition in tumor microenvironment", Cancer Science, 2023.
DOI: 10.1111/cas.16045
J Cacheux, J Ordonez-Miranda, A Bancaud, L Jalabert, M Nomura, YT Matsunaga, "Asymmetry of tensile versus compressive elasticity and permeability contributes to the regulation of exchanges in collagen gels", Science Advances, 2023.
DOI: 10.1126/sciadv.adf9775
J Cacheux, A Bancaud, D Alcaide, JI Suehiro, Y Akimoto, H Sakurai, YT Matsunaga, "Endothelial tissue remodeling induced by intraluminal pressure enhances paracellular solute transport", iScience, 2023.
DOI: 10.1016/j.isci.2023.107141
D Alcaide, J Cacheux, A Bancaud, R Muramatsu, YT Matsunaga, "Solute transport in the brain tissue: What are the key biophysical parameters tying in vivo and in vitro studies together?", Biomaterials Science, 2023, 11, 3450 - 3460.
DOI: 10.1039/D3BM00027C
桜庭大樹, 中島忠章, 阿部卓哉, 二階堂沙紀, 山口芳正, 佐野貴規, 松永行子, "壁細胞を有する三次元人工微小血管モデルを用いたヒハツエキス，イチョウ葉エキス配合食品の血管透過性に対する評価", 生産研究, 75(1), 111-114 (2023).
DOI: 10.11188/seisankenkyu.75.111
S Nakano, A Uyeda, Y. T. Matsunaga, R Muramatsu, "Phenotypic and transcriptional characterization of oligodendrocyte precursor cells in a 3D culture", Biomaterials Science, 11, 2860-2869 (2023).
DOI: 10.1039/D2BM01897G
K. Doi, H. Kimura, S.H. Kim, S. Kaneda, T. Wada, T. Tanaka, A. Shimizu, T. Sano, M. Chikamori, M. Shinohara, Y.T. Matsunaga, M. Nangaku, T. Fujii, "Enhanced podocyte differentiation and changing drug toxicity sensitivity through pressure controlled mechanical filtrating stress on a glomerulus-on-a-chip", Lab on a Chip, 23, 437-450 (2023) *selected as a back cover
DOI: 10.1039/D2LC00941B

2022

T. Sano, T. Nakajima, K.A. Senda, S. Nakano, M. Yamato, Y. Ikeda, H. Zeng, J.I. Kawabe, Y.T. Matsunaga "Image-Based Crosstalk Analysis of Cell-Cell Interactions during Sprouting Angiogenesis using Blood-Vessel-on-a-Chip", Stem Cell Research & Therapy, 13, 532 (2022).
DOI: 10.1186/s13287-022-03223-1
佐野貴規, 松永行子, "微小血管モデルを用いた血管組織の再構成・可視化・定量化", バイオマテリアル-生体材料-, 40-4, pp.306-311, (2022).
近森正智, 南学正臣, 藤井輝夫, 松永行子, "「臓器チップ」の開発と食品開発への応用", 月刊フードケミカル, 9, pp.79-82, (2022).
松永行子, Part II 血管・リンパ管の最先端研究："第13章組織工学的血管再生", 血管・リンパ管の機能制御と疾患メカニズム, 分担執筆, (2022).
T. Nakajima, S. Nakano, A. Kikuchi, Y.T. Matsunaga, "Nailfold capillary patterns correlate with age, gender, lifestyle habits, and fingertip temperature", PLOS ONE 17(6), e0269661, (2022).
DOI: 10.1371/journal.pone.0269661
Yukinori Ikeda, Kazuki Takahashi, Tetsuro Watabe, Y.T. Matsunaga, "がん微小環境における脈管系の役割とin vitro モデルの有用性", membrane 47(3), pp.161-168, (2022).
DOI: 10.5360/membrane.47.161
Shizuka Nakano, Rieko Muramatsu, Y.T. Matsunaga, "Designing in-vitro systems for studying central nervous system diseases", Seisan-Kenkyu 74(2), pp.147-151, (2022).
DOI: 10.11188/seisankenkyu.74.147
Kotaro Doi, Hiroshi Kimura, Y.T. Matsunaga, Teruo Fujii, Masaomi Nangaku, "Glomerulus-on-a-Chip: Current Insights and Future Potential Towards Recapitulating Selectively Permeable Filtration Systems", International Journal of Nephrology and Renovascular Disease, 15, pp.85-101, (2022).
DOI: 10.2147/IJNRD.S344725

2021

Joris Pauty, Shizuka Nakano, Ryo Usuba, Tadaaki Nakajima, Yoshikazu Johmura, Satotaka Omori, Naoya Sakamoto, Akihiko Kikuchi, Makoto Nakanishi, Y.T. Matsunaga, "A 3D Tissue Model-On-A-Chip for Studying the Effects of Human Senescent Fibroblasts on Blood Vessels", Biomaterials Science, 9, pp.199-211, (2021).
DOI: 10.1039/d0bm01297a

2020

H. Sandhu, Y.T. Matsunaga, "Wellbeingと工学―人文科学と実現するWellbeing支援―", Seisan-Kenkyu 72(5), pp.367-370,(2020).
DOI: 10.11188/seisankenkyu.72.367
Tadaaki Nakajima, Katsunori Sasaki, Akihiro Yamamori, Kengo Sakurai, Kaori Miyata, Tomoyuki Watanabe, Yukiko T. Matsunaga, “A simple three-dimensional gut model constructed in a restricted ductal microspace induces intestinal epithelial cell integrity and facilitates absorption assays", Biomaterials Science, 8, pp.5615-5627, (2020). (selected as a back cover)
DOI: 10.1039/D0BM00763C
Y. Ikeda, Y.T. Matsunaga, “血行性転移時の細胞動態解明に向けた生体模倣血管モデルによるアプローチの現状/Introduction of In Vitro Microvessel Model for Understanding Cellular Dynamics on Cancer Metastasis", Seisan-Kenkyu 72(3), pp.261-267,(2020). (selected as a cover)
DOI: 10.11188/seisankenkyu.72.261
Y. Yoshimatsu*, S. Kimuro*, J. Pauty, K. Takagaki, S. Nomiyama, A. Inagawa, K. Maeda, K.A. Podyma-Inoue, K. Kajiya, Y.T. Matsunaga, T. Watabe, “TGF-β and TNF-α Cooperatively Induce Mesenchymal Transition of Lymphatic Endothelial Cells via Activation of Activin Signals", PLOS ONE, 15, e0232356, (2020) (*equally contributed) .
DOI: 10.1371/journal.pone.0232356

2019

N. Bidan, J. Bailleul-Dubois, J. Duval, M. Winter, M. Denoulet, K. Hannebicque, IY El-Sayed, C. Ginestier, V. Forissier, Y.T. Matsunaga, S. Meignan, F. Anquez, S. Julien, A. Bonnefond, M. Derhourhi, X.L., Bourhis, C. Lagadec, "Transcriptomic Analysis of Breast Cancer Stem Cells and Development of a pALDH1A1:mNeptune Reporter System for Live Tracking.", Proteomics, e1800454, (2019).
DOI: 10.1002/pmic.201800454
R. Usuba, Y.T. Matsunaga, "微小血管モデルを利用したがん微小環境の模倣と遺伝子機能探索への展開", Seisan-Kenkyu 71(4), pp. 775-781, 2019. (Research Review, in Japanese)
DOI:10.11188/seisankenkyu.71.775
Y.T. Matsunaga, "前臨床試験へむけた抗血管新生治療薬評価のための三次元微小血管モデル 3D microvessel model for evaluating anti-angiogenic drugs towards preclinical study", リンパ学会機関誌, 42 (1), pp.28-31, (2019).
Tadaaki NAKAJIMA, Y.T. Matsunaga, "三次元人工微小血管モデルによる血管内皮細胞のフェノタイプ解析 Phenotypic analysis of endothelial cell function by using three-dimensional microvessel model", 日本血栓止血学会誌, 30 (3), pp.512-520, (2019).
DOI: 10.2491/jjsth.30.512
R. Usuba, J. Pauty, F. Soncin, Y.T. Matsunaga, "EGFL7 Regulates Sprouting Angiogenesis and Endothelial Integrity in a Human Blood Vessel Model", Biomaterials, 197, pp.305-316, (2019).
DOI: 10.1016/j.biomaterials.2019.01.022

2018

H. Ryu, Y. Morita, Y.T. Matsunaga, "How did the word of ‘architecture’ spread in academic literature? (Part.2) -Through comparison with ‘structure’.-", Seisan-Kenkyu 70(3), pp.209-213, (2018).
DOI: 10.11188/seisankenkyu.70.209
E. Lee, H. Takahashi, J. Pauty, M. Kobayashi, K. Kato, K. Kabara, J. Kawabe, Y.T. Matsunaga, "3D in vitro pericyte-supported microvesel model: Visualisation and quantitative characterisation of multistep angiogenesis", J. Mater. Chem. B, 6, pp.1085-1094, (2018).
DOI: 10.1039/C7TB03239K
J. Pauty, R. Usuba, I.G. Cheng, L. Hespel, H. Takahashi, K. Kato, M. Kobayashi, H. Nakajima, E. Lee, F. Yger, F. Soncin, Y.T. Matsunaga, "A vascular endothelial growth factor-dependent sprouting angiogenesis assay based on an in vitro human blood vessel model for the study of anti-angiogenic drugs", EBioMedicine, pp.225-236, (2018).
DOI: 10.1016/j.ebiom.2017.12.014.

2017

S. Tachizawa*, H. Takahashi*, Y.J. Kim, A. Odawara, J. Pauty, Y. Ikeuchi, I. Suzuki, A. Kikuchi, Y.T. Matsunaga, "Bundle gel fibers with tunable microenvironment for in vitro neuron cell guiding", ACS Appl. Mater. Interfaces, 9(49), pp.43250-43257, (2017). (*: equal contribution)
DOI: 10.1021/acsami.7b14585
H. Takahashi, K. Kato, M. Kobayashi, K. Ueyama, Y.T. Matsunaga, "Live imaging of 3D in vitro angiogenesis model by OCT technique",Seisan-Kenkyu 69(3), pp.123-126, 2017. (Research Review, in Japanese)
DOI: 10.11188/seisankenkyu.69.123
R. Usuba, J. Pauty, H. Takahashi, JI Suehiro, Y.T. Matsunaga, "An in vitro micro vessel model mimicking the inflammatory condition for evaluation of barrier function", Seisan-Kenkyu 69(3), pp.123-126, 2017. (Research Review, in Japanese)
DOI: 10.11188/seisankenkyu.69.127
H. Ryu, Y. Morita, Y.T. Matsunaga, "How did the word of "architecture" spread in academic literature? (No.1)", Seisan-Kenkyu 67(3), pp.133-136, 2017.
DOI: 10.11188/seisankenkyu.69.133
Y.J. Kim, Y.T. Matsunaga, "Thermo-responsive polymers and their application as smart biomaterials", J. Mater. Chem. B, 2017, 5, pp.4307-4321, selected as "2017 Journal of Materials Chemistry B HOT Papers and Journal of Materials Chemistry B Emerging Investigators"
DOI: 10.1039/C7TB00157F.
H. Takahashi, K. Kato, K. Ueyama, M. Kobayashi, G. Baik, Y. Yukawa, J. Suehiro, Y.T. Matsunaga, "Visualizing dynamics of angiogenic sprouting from a three-dimensional microvasculature model using stage-top optical coherence tomography", Scientific Reports 7, pp.42426, (2017).
DOI: 10.1038/srep42426.
J. Pauty*, R. Usuba*, H. Takahashi, J. Suehiro, K. Fujisawa, K. Yano, T. Nishizawa, Y.T. Matsunaga, "A vascular permeability assay using an in vitro human microvessel model mimicking the inflammatory condition", Nanotheranostics, 1(1), pp.103-113, (2017). (*: equal contribution)
DOI:10.7150/ntno.18303.
R. Usuba, N. Sasaki, Y.T. Matsunaga, "Control of Cellular Attachment Using a Bundled Hydrogel Fiber", Journal of the Surface Science Society of Japan,
DOI: 10.1380/jsssj.38.83.

2016

A. Tan, K. Fujisawa, Y. Yukawa, Y.T. Matsunaga, "Bottom-up fabrication of artery-mimicking tubular co-cultures in collagen-based microchannel scaffolds", Biomaterials Science, 4, pp.1503-1514, (2016).
DOI: 10.1039/C6BM00340K.
S. Tachizawa, H. Takahashi and Y.T. Matsunaga, "Fabrication of the bundled gel fibers for regenerative medicine", Seisan-Kenkyu 68(3), pp.3-7, 2016. (Research Review, in Japanese)
Y.J. Kim, S. Yamamoto, H. Takahashi, N. Sasaki and Y.T. Matsunaga, "Multiwall Carbon Nanotube Reinforced Biomimetic Bundled Gel Fibre", Biomaterials Science, 4, pp.1197-1201, (2016). (selected as a back cover)
DOI: 10.1039/c6bm00292g.
Y.J. Kim, S.H. Kim, T. Fujii, and Y.T. Matsunaga, "Dual Stimuli-Responsive Smart Beads that Allow "On–Off" Manipulation of Cancer Cells", Biomaterials Science, 4, pp.953-957, (2016).
DOI: 10.1039/c6bm00186f.
Y.J. Kim, M. Tachibana, M. Umezu and Y.T. Matsunaga, "Bio-Inspired Smart Hydrogel with Temperature-dependent Properties and Enhanced Cell Attachment", Journal of Materials Chemistry B, 4, pp.1740-1746, (2016).
DOI:10.1039/C5TB02735G

2015

Y.J. Kim*, Y. Takahashi*, N. Kato and Y.T. Matsunaga, "Fabrication of Biomimetic Bundled Gel Fibres Using Dynamic Microfluidic Gelation of Phase-Separated Polymer Solutions", Journal of Materials Chemistry B, 3, pp.8154-8161 (2015). (*: equal contribution)
Y. Yukawa, K. Fujisawa, B. Kim, Y. T. Matsunaga, "Observation of endothelial cell behavior within in vitro 3D microvasculature under shear stress", Seisan-Kenkyu 67(3), pp.251-253 (2015).
K. Fujisawa, I. Matsuda, J.I. Suehiro, Y. Yukawa, M. Umezu, Y. T. Matsunaga, "Novel 3D in vitro model for evaluating vascular permeability", Seisan-Kenkyu 67(3), pp.255-257 (2015).

2013

H. Onoe, T. Okitsu, A. Itou, M. Kato-Negishi, R. Gojo, D. Kiriya, K. Sato, S. Mirua, S. Iwanaga, K. Kuribayashi-Shigetomi, Y.T. Matsunaga, Y. Shimoyama, and S. Takeuchi, "Metre-long Cell-laden Microfibres Exhibit Tissue Morphologies and Functions", Nature Materials, 12, pp.584–590 (2013).

2011

Tomoaki Kurakazu, Kaori Kuribayashi-Shigetomi, Yukiko T. Matsunaga, Hiroshi Kimura, Teruo Fujii, Yasuyuki Sakai and Shoji Takeuchi, "Selective Retrieval of Microparticles in Microchambers using Electrolytically Generated Bubbles for Cell Array Applications", Sensors and Actuators B, vol. 159(1), pp.229-233, (2011).
DOI: 10.1016/j.snb.2011.06.077
Y.T. Matsunaga*, Y. Morimoto*, and Shoji Takeuchi, "Molding cell beads for rapid construction of macroscopic 3D tissue architecture", Advanced Materials, 23, H90-H94 (2011). (*: equal contribution)
* seleced as a cover of Advanced Healthcare Materials.

2010

H. Shibata*, Y.J. Heo*, T. Okitsu, Y. Matsunaga, T. Kawanishi, S. Takeuchi, "Injectable hydrogel microbeads for fluorescence-based continuous glucose monitoring", Proc. Natl. Acad. Sci. USA., 107, pp.17894-17898, (2010). (*: equal contribution)
M. Negishi-Kato, Y. Tsuda, H. Onoe, S. Takeuchi, "A neurospheroid network-stamping method for neural transplantation to the brain", Biomaterials, 31, pp.8939-8945, (2010).
DOI: 10.1016/j.biomaterials.2010.08.008
K. Kuribayashi, Y. Tsuda, H. Nakamura, S. Takeuchi, "Micro-patterning of phosphorylcholine-based polymer in a microfluidic channel", Sensors and Actuators B, 149, pp.177-183, (2010).
N. Asakawa, T. Shimizu, Y. Tsuda, S. Sekiya, T. Sasagawa, M. Yamato, F. Fukai, T. Okano, "Pre-vascularization of in vitro three-dimensional tissues created by cell sheet engineering", Biomaterials, 31, pp.3903-3909, (2010).
DOI: 10.1016/j.biomaterials.2010.01.105
Y. Tsuda, Y. Morimoto, S. Takeuchi, "Monodisperse cell-encapsulating peptide microgel beads for 3D cell culture", Langmuir, 26, pp.2645-2649, (2010).
DOI: 10.1021/la902827y

2009

Y. Morimoto, W.H. Tan, Y. Tsuda, S. Takeuchi, "Monodisperse semi-permeable microcapsules for continuous observation of cells", Lab on a Chip, 9, pp.2217-2223, (2009).
DOI: 10.1039/b900035f
D. Sasaki, T. Shimizu, S. Masuda, J. Kobayashi, K. Itoga, Y. Tsuda, J.K. Yamashita, M. Yamato, T. Okano, "Mass preparation of size-controlled mouse embryonic stem cell aggregates and induction of cardiac differentiation by cell patterning method", Biomaterials, 30, pp.4384-4389 (2009).
DOI: 10.1016/j.biomaterials.2009.05.003
J. Yang, M. Yamato, H. Sekine, S. Sekiya, Y. Tsuda, K. T. Shimizu and T. Okano, "Tissue Engineering Using Laminar Cellular Assemblies", Advanced Materials, 21, pp.1-6 (2009).
DOI: 10.1002/adma.200801990

2008

C. Williams, Y. Tsuda, B. C. Isenberg, M. Yamato, T. Shimizu, T. Okano, J. Y. Wong, "Aligned Cell Sheets Grown on Thermo-Responsive Substrates with Micro-Contact Printed Protein Patterns", Advanced Materials, 20, pp.1-5, (2008).
K. Itoga, J. Kobayashi, Y. Tsuda, M. Yamato, T. Okano, "Second-generation maskless photolithography device for surface micropatterning and microfluidic channel fabrication", Analytical Chemistry, 80, pp.1323-1327, (2008).
DOI: 10.1021/ac702208d

2007

B.C. Isenberg, Y. Tsuda, C. Williams, T. Shimizu, M. Yamato, T. Okano, J.Y. Wong, "A thermoresponsive, microtextured substrate for cell sheet engineering with defined structural organization", Biomaterials, 29, pp.2565-2572,(2007).
DOI: 10.1016/j.biomaterials.2008.02.023
Y. Tsuda, T. Shimizu, M. Yamato, A. Kikuchi, T. Sasagawa, S. Sekiya, J. Kobayashi, G. Chen and T. Okano, "Thermo-responsive Microtextured Culture Surfaces Facilitate Fabrication of Capillary Networks", Advanced Materials, 19, pp.3633-3636, (2007).
Y. Tsuda, T. Shimizu, M. Yamato, A. Kikuchi, T. Sasagawa, S. Sekiya, J. Kobayashi, G. Chen and T. Okano, "Cellular Control of Tissue Architectures Using a Three-dimensional Tissue Fabrication Technique", Biomaterials, 33, pp.4939-4946,(2007).
DOI: 10.1016/j.biomaterials.2007.08.002
M. Yamada, K. Kano, Y. Tsuda, J. Kobayashi, M. Yamato, M. Seki and T. Okano, "Microfluidic Devices for Size-dependent Separation of Liver Cells", Biomed. Microdev. 9, pp.637-645, (2007).
DOI: 10.1007/s10544-007-9055-5

2006

Y. Tsuda, A. Kikuchi, M. Yamato, G. Chen and T. Okano, "Heterotypic Cell Interactions on a Dually Patterned Surface", Biochem. Biophys. Res. Commun., 348, pp.937-944, (2006).
DOI: 10.1016/j.bbrc.2006.07.138

2005

Y. Tsuda, A. Kikuchi, M. Yamato, Y. Sakurai, M. Umezu, and T. Okano, "The Use of Patterned Dual Thermoresponsive Surfaces for the Collective Recovery as Co-Cultured Cell Sheets", Biomaterials, 26, pp.1885-1893, (2005).
DOI: 10.1016/j.biomaterials.2004.06.005

2004

Y. Tsuda, A. Kikuchi, M. Yamato, Y. Sakurai, M. Umezu, and T. Okano, "Control of Cell Adhesion and Detachment Using Temperature and Thermo-responsive Copolymer Grafted Culture Surfaces", J. Biomed. Mater. Res., 69A, pp.70-78, (2004).